BDBM50109613 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenethyl-phosphinic acid ethyl ester::CHEMBL175164
SMILES CCOP(=O)(CCc1ccccc1)N1Cc2ccccc2CC1C(=O)NO
InChI Key InChIKey=DWFUVVZGNJNHKO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50109613
Affinity DataKi: 11.6nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nippon Organon K.K.
Curated by ChEMBL
Nippon Organon K.K.
Curated by ChEMBL
Affinity DataKi: 14.2nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
Affinity DataKi: 20.8nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
Affinity DataKi: 38.3nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nippon Organon K.K.
Curated by ChEMBL
Nippon Organon K.K.
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair