BDBM50109647 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)::CHEMBL1346::DARIFENACIN::DARIFENACIN HYDROBROMIDE::Enablex

SMILES: NC(=O)C([C@@H]1CCN(CCc2ccc3OCCc3c2)C1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=HXGBXQDTNZMWGS-UHFFFAOYSA-N

Data: 19 KI  6 IC50  1 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50109647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily D member 3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily E/KQT member 1 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor (Guinea pig)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Rat)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Rat)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Rat)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50109647 (Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...) Show SMILES Show InChI	GoogleScholar	UniChem		63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair