BDBM50109771 3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carbonyl}-2-methyl-propylcarbamoyl)-methoxy]-phenylsulfanyl}-2,2-dimethyl-propionic acid::CHEMBL152817

SMILES CC(C)[C@H](NC(=O)COc1ccc(SCC(C)(C)C(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2ccccc2o1

InChI Key InChIKey=VAHHJSDAHDMGCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109771   

TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109771(3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed