BDBM50110164 (Z)-2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid::2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid::CHEMBL18797::SULINDAC SULFIDE::Sulindac sulphide::[6-Fluoro-2-methyl-3-(4-methylsulfanyl-benzylidene)-3H-inden-1-yl]-acetic acid::cid_5352624::{6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid::{6-Fluoro-2-methyl-3-[1-[4-(methyl-lambda*4*-sulfanyl)-phenyl]-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid

SMILES: CC\1=C(c2cc(ccc2/C1=C\c3ccc(cc3)SC)F)CC(=O)O

InChI Key: InChIKey=LFWHFZJPXXOYNR-UHFFFAOYSA-N

Data: 8 KI  10 IC50  10 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50110164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [1-37] (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division control protein 42 homolog (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
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Ras-related protein Rab-2A (Dog)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.47E+4	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Sheep)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.33E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
GTPase KRas [1-37] (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras-related protein Rab-7a (Dog)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.12E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division control protein 42 homolog (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras-related protein Rab-7a (Dog)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Prostaglandin D2 receptor 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division control protein 42 homolog (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50110164 ({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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