BDBM50110455 6-(2-Chlorophenyl)-3-[4-[(E/Z)-6-ethoxycarbonyl-1-(3-pyridyl)-1-hexenyl]phenylmethyl]-8,11-dimethyl-2,3,4,5-tetrahydro-8H-pyrido[4',3':4,5]-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine::CHEMBL349150

SMILES CCOC(=O)CCCC\C=C(/c1ccc(CN2CCc3c(C2)sc-2c3C(=NC(C)c3nnc(C)n-23)c2ccccc2Cl)cc1)c1cccnc1

InChI Key InChIKey=GCTAXPRQXHZAPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110455   

TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50110455(6-(2-Chlorophenyl)-3-[4-[(E/Z)-6-ethoxycarbonyl-1-...)
Affinity DataIC50: 72nMAssay Description:In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed