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BDBM50110679 CHEMBL3605829

SMILES: CCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1

InChI Key: InChIKey=JLIGIWZNIGGFNJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM50110679
PNG
(CHEMBL3605829)
Show SMILES CCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1
Show InChI InChI=1S/C28H32FN3O4S/c1-5-14-36-23-11-13-26(25(29)16-23)31-37(34,35)24-12-6-19-17-32(18-20(19)15-24)27(33)30-22-9-7-21(8-10-22)28(2,3)4/h6-13,15-16,31H,5,14,17-18H2,1-4H3,(H,30,33)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.98E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...


Bioorg Med Chem 23: 5922-31 (2015)


Article DOI: 10.1016/j.bmc.2015.06.065
BindingDB Entry DOI: 10.7270/Q2639RJ6
More data for this
Ligand-Target Pair