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BDBM50110998 2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-oxazol-5-yl]-benzenesulfonamide::CHEMBL284761

SMILES: Cc1ccc(s1)-c1nc(C)oc1-c1ccc(c(F)c1)S(N)(=O)=O

InChI Key: InChIKey=DODVNPBCMKADSZ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110998   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1 (COX-1)


(Homo sapiens (Human))
BDBM50110998
PNG
(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Show SMILES Cc1ccc(s1)-c1nc(C)oc1-c1ccc(c(F)c1)S(N)(=O)=O
Show InChI InChI=1S/C15H13FN2O3S2/c1-8-3-5-12(22-8)14-15(21-9(2)18-14)10-4-6-13(11(16)7-10)23(17,19)20/h3-7H,1-2H3,(H2,17,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Central Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human purified Prostaglandin G/H synthase 1


J Med Chem 45: 1511-7 (2002)


Article DOI: 10.1021/jm010484p
BindingDB Entry DOI: 10.7270/Q2H995XZ
More data for this
Ligand-Target Pair
Cyclooxygenase


(Homo sapiens (Human))
BDBM50110998
PNG
(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Show SMILES Cc1ccc(s1)-c1nc(C)oc1-c1ccc(c(F)c1)S(N)(=O)=O
Show InChI InChI=1S/C15H13FN2O3S2/c1-8-3-5-12(22-8)14-15(21-9(2)18-14)10-4-6-13(11(16)7-10)23(17,19)20/h3-7H,1-2H3,(H2,17,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Central Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human purified Prostaglandin G/H synthase 2


J Med Chem 45: 1511-7 (2002)


Article DOI: 10.1021/jm010484p
BindingDB Entry DOI: 10.7270/Q2H995XZ
More data for this
Ligand-Target Pair