BindingDB logo
myBDB logout

BDBM50111337 CHEMBL11816::N,N-Dimethyl-2-{4-[1'-(naphthalene-1-carbonyl)-[1,4']bipiperidinyl-4-ylmethyl]-phenylsulfanyl}-acetamide

SMILES: CN(C)C(=O)CSc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ccccc23)cc1

InChI Key: InChIKey=BNSBZDKOVZMVMW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111337   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50111337
PNG
(CHEMBL11816 | N,N-Dimethyl-2-{4-[1'-(naphthalene-1...)
Show SMILES CN(C)C(=O)CSc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ccccc23)cc1
Show InChI InChI=1S/C32H39N3O2S/c1-33(2)31(36)23-38-28-12-10-24(11-13-28)22-25-14-18-34(19-15-25)27-16-20-35(21-17-27)32(37)30-9-5-7-26-6-3-4-8-29(26)30/h3-13,25,27H,14-23H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.


Bioorg Med Chem Lett 12: 1087-91 (2002)


Article DOI: 10.1016/s0960-894x(02)00096-3
BindingDB Entry DOI: 10.7270/Q2MS3S2P
More data for this
Ligand-Target Pair