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BDBM50111414 3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-carbonyl)-piperidin-1-yl]-butyric acid::CHEMBL276482

SMILES: CC(CC(O)=O)N1CCC(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1

InChI Key: InChIKey=IAGDYZSYUXWMJO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111414   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50111414
PNG
(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Show SMILES CC(CC(O)=O)N1CCC(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1
Show InChI InChI=1/C23H34N4O3/c1-18(16-21(28)29)25-11-4-19(5-12-25)22(30)26-13-6-23(7-14-26)8-15-27(17-23)20-2-9-24-10-3-20/h2-3,9-10,18-19H,4-8,11-17H2,1H3,(H,28,29)
PDB

KEGG

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PC sid
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Patents


Similars

Article
PubMed
n/an/a 225n/an/an/an/an/an/a



COR Therapeutics Inc

Curated by ChEMBL


Assay Description
In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.


Bioorg Med Chem Lett 12: 1103-7 (2002)


Article DOI: 10.1016/s0960-894x(02)00095-1
BindingDB Entry DOI: 10.7270/Q2H131BN
More data for this
Ligand-Target Pair