BDBM50111591 4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benzene-1,2-diol::CHEMBL34034

SMILES: Oc1ccc(cc1O)-c1csc(Nc2ccc(F)cc2F)n1

InChI Key: InChIKey=GFUKFZXSGYDXIF-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50111591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Escherichia coli (strain K12))	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Escherichia coli (strain K12))	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsin-C (Human)	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-galactosidase (Human)	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Escherichia coli (strain K12))	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Chicken)	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Malate dehydrogenase (Thermus thermophilus)	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen B (Human)	BDBM50111591 (4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair