BindingDB logo
myBDB logout

BDBM50112035 4-Amino-N-{1-[1-(3-amino-2-hydroxy-propyl)-piperidin-4-ylmethyl]-piperidin-4-yl}-5-chloro-2-methoxy-benzamide::CHEMBL433984

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC(O)CN)CC2)CC1

InChI Key: InChIKey=PNAYGRSQMBUGLN-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112035   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HTR4


(GUINEA PIG)
BDBM50112035
PNG
(4-Amino-N-{1-[1-(3-amino-2-hydroxy-propyl)-piperid...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC(O)CN)CC2)CC1
Show InChI InChI=1/C22H36ClN5O3/c1-31-21-11-20(25)19(23)10-18(21)22(30)26-16-4-8-27(9-5-16)13-15-2-6-28(7-3-15)14-17(29)12-24/h10-11,15-17,29H,2-9,12-14,24-25H2,1H3,(H,26,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand


Bioorg Med Chem Lett 12: 967-70 (2002)


Article DOI: 10.1016/s0960-894x(02)00060-4
BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair