BDBM50112153 CHEMBL3608402::US9464044, 83

SMILES CC(C)(NS(=O)(=O)c1cc(F)cc(F)c1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O

InChI Key InChIKey=ZXNJFMYNNXCBLV-ACPSHBDFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112153   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112153(CHEMBL3608402 | US9464044, 83)
Affinity DataIC50:  9.90nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112153(CHEMBL3608402 | US9464044, 83)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112153(CHEMBL3608402 | US9464044, 83)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed