BDBM50112205 CHEMBL298335::N-[2-(5-Methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acetamide

SMILES COc1cc2c(CCNC(C)=O)c[nH]c2cc1[N+]([O-])=O

InChI Key InChIKey=BCLGLBCJLIBAHF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112205   

TargetMelatonin receptor type 1B(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50112205(N-[2-(5-Methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acet...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1B expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50112205(N-[2-(5-Methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acet...)
Affinity DataKi:  15nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50112205(N-[2-(5-Methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acet...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to Melatonin receptor 3 (MT3) of Syrian hamster brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed