BDBM50112353 CHEMBL3609329

SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2N(C)c2ccc(Cl)cc12

InChI Key InChIKey=DGBFDSJYMVTWOH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50112353   

TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112353(CHEMBL3609329)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PAK1 (unknown origin) in presence of 150 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112353(CHEMBL3609329)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PAK1 (unknown origin) in presence of 15 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112353(CHEMBL3609329)
Affinity DataIC50:  900nMAssay Description:Inhibition of wild type dephosphorylated form of PAK1 (249 to 545) (unknown origin) expressed in Escherichia coli using 5-Fluo-Ahx-AKRRRLSSLRA-COOH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112353(CHEMBL3609329)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of wild type phosphorylated form of PAK1 (249 to 545) (unknown origin) expressed in Escherichia coli using 5-Fluo-Ahx-AKRRRLSSLRA-COOH as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112353(CHEMBL3609329)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PAK1 (unknown origin) in presence of 1.5 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed