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BDBM50112608 CHEMBL3609384

SMILES: CCS(=O)(=O)c1ccc(CC(=O)Nc2ncc(s2)-c2cc(Cl)ccc2Cl)cc1

InChI Key: InChIKey=LTCJRWAYCKKPMR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112608   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM50112608
PNG
(CHEMBL3609384)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ncc(s2)-c2cc(Cl)ccc2Cl)cc1
Show InChI InChI=1S/C19H16Cl2N2O3S2/c1-2-28(25,26)14-6-3-12(4-7-14)9-18(24)23-19-22-11-17(27-19)15-10-13(20)5-8-16(15)21/h3-8,10-11H,2,9H2,1H3,(H,22,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a<2.51E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of RORgammat (unknown origin) assessed as inhibition of agonist-induced response by FRET assay


ACS Med Chem Lett 6: 787-92 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00122
BindingDB Entry DOI: 10.7270/Q2XG9SWD
More data for this
Ligand-Target Pair