BDBM50112678 (R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-phenyl)-2H-chromene-3-carboxylic acid::2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-phenyl)-2H-chromene-3-carboxylic acid::CHEMBL61211

SMILES COc1ccc(cc1)C1=C([C@H](Oc2ccc(OC(C)C)cc12)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=BATSJXIVNKJCKQ-AREMUKBSSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50112678   

TargetEndothelin receptor type B(Sus scrofa)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  120nMAssay Description:Binding affinity to endothelin B receptor measured by inhibition of [125I]-ET-3 binding recombinant pig ET-B receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  200nMAssay Description:Binding affinity at human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.190nMAssay Description:Displacement of [125I]ET-1 from ET-A receptor in RASMC incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.450nMAssay Description:Binding affinity at human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.190nMAssay Description:Ability to displace [125I]-ET-1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50112678((R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-meth...)
Affinity DataIC50:  0.190nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed