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BDBM50112922 4-(2-Bromo-phenoxy)-imidazo[1,5-a]quinoxaline::4-(2-bromophenoxy)imidazo[1,5-a]quinoxaline::CHEMBL287214

SMILES: Brc1ccccc1Oc1nc2ccccc2n2cncc12

InChI Key: InChIKey=KFDAGDRVPWWLRT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112922   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRC


(Homo sapiens (Human))
BDBM50112922
PNG
(4-(2-Bromo-phenoxy)-imidazo[1,5-a]quinoxaline | 4-...)
Show SMILES Brc1ccccc1Oc1nc2ccccc2n2cncc12
Show InChI InChI=1S/C16H10BrN3O/c17-11-5-1-4-8-15(11)21-16-14-9-18-10-20(14)13-7-3-2-6-12(13)19-16/h1-10H
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



University of Zurich

Curated by ChEMBL


Assay Description
Inhibition of Lck


J Med Chem 51: 1179-88 (2008)


Article DOI: 10.1021/jm070654j
BindingDB Entry DOI: 10.7270/Q29Z95RD
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM50112922
PNG
(4-(2-Bromo-phenoxy)-imidazo[1,5-a]quinoxaline | 4-...)
Show SMILES Brc1ccccc1Oc1nc2ccccc2n2cncc12
Show InChI InChI=1S/C16H10BrN3O/c17-11-5-1-4-8-15(11)21-16-14-9-18-10-20(14)13-7-3-2-6-12(13)19-16/h1-10H
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...


Bioorg Med Chem Lett 12: 1361-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00191-9
BindingDB Entry DOI: 10.7270/Q2R78DJ1
More data for this
Ligand-Target Pair