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BDBM50113396 4-[(R)-2-(3-cyclopentyloxy-4-methoxy-phenyl)-2-pyridin-4-yl-ethyl]-pyridine::CHEMBL36007

SMILES: COc1ccc(cc1OC1CCCC1)[C@H](Cc1ccncc1)c1ccncc1

InChI Key: InChIKey=VTEPWFOMRKHXNI-JOCHJYFZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113396   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))
BDBM50113396
PNG
(4-[(R)-2-(3-cyclopentyloxy-4-methoxy-phenyl)-2-pyr...)
Show SMILES COc1ccc(cc1OC1CCCC1)[C@H](Cc1ccncc1)c1ccncc1
Show InChI InChI=1S/C24H26N2O2/c1-27-23-7-6-20(17-24(23)28-21-4-2-3-5-21)22(19-10-14-26-15-11-19)16-18-8-12-25-13-9-18/h6-15,17,21-22H,2-5,16H2,1H3/t22-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Celltech R&D Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant phosphodiesterase 4A


Bioorg Med Chem Lett 12: 1451-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00202-0
BindingDB Entry DOI: 10.7270/Q22J6B5D
More data for this
Ligand-Target Pair