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BDBM50113456 CHEMBL3605987

SMILES: CC(=O)N1CCC(CC1)N1Cc2cccc(C(N)=O)c2C1=O

InChI Key: InChIKey=CMCZUAADWXQMGN-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM50113456
PNG
(CHEMBL3605987)
Show SMILES CC(=O)N1CCC(CC1)N1Cc2cccc(C(N)=O)c2C1=O
Show InChI InChI=1S/C16H19N3O3/c1-10(20)18-7-5-12(6-8-18)19-9-11-3-2-4-13(15(17)21)14(11)16(19)22/h2-4,12H,5-9H2,1H3,(H2,17,21)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 250n/an/an/an/an/a



Nerviano Medical Sciences srl

Curated by ChEMBL


Assay Description
Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assay


J Med Chem 58: 6875-98 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00680
BindingDB Entry DOI: 10.7270/Q2JD4ZKF
More data for this
Ligand-Target Pair