BDBM50113468 CHEMBL3603915::US10246432, Example 15::US10584111, Ex No. 15::US11584732, Example 15

SMILES: c1cnn(c1)c2cc(ncn2)c3cc(cc(c3F)Cl)C#N

InChI Key: InChIKey=UPDNOLJVPHHECL-UHFFFAOYSA-N

Data: 7 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50113468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50113468 (CHEMBL3603915 | US10246432, Example 15 | US1058411...) Show SMILES Show InChI	GoogleScholar	UniChem		0.832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair