BDBM50113519 CHEMBL3604645

SMILES CC(C)Oc1cc(C2CNC2)c(C)cc1Nc1ncc(Cl)c(Nc2cn(C)nc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=RUCMNKAAZBJVHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113519   

TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113519(CHEMBL3604645)
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type human recombinant ALK using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113519(CHEMBL3604645)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2016
Entry Details Article
PubMed