BDBM50113745 3-[6-(3-Chloro-phenylamino)-9-isopropyl-9H-purin-2-ylamino]-propan-1-ol::CHEMBL80895::cid_16746117

SMILES CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCCO)nc12

InChI Key InChIKey=IGKKQXCKNSJVEA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113745   

TargetSerine/threonine-protein kinase 33(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50113745(CHEMBL80895 | cid_16746117 | 3-[6-(3-Chloro-phenyl...)
Affinity DataEC50:  1.84E+3nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50113745(CHEMBL80895 | cid_16746117 | 3-[6-(3-Chloro-phenyl...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50113745(CHEMBL80895 | cid_16746117 | 3-[6-(3-Chloro-phenyl...)
Affinity DataIC50: 9.00E+5nMAssay Description:Binding affinity to cyclin-dependent kinase 1 (CDK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed