BDBM50114433 2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL44830

SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1cc2ccccc2cc1S(C)(=O)=O

InChI Key InChIKey=RGWARUXYVDMFDB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50114433   

TargetKallikrein-1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114433(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed