BDBM50114532 (R)-2-{[(Biphenyl-4-carbonyl)-amino]-methyl}-3-(3-carbamimidoyl-phenyl)-propionic acid methyl ester::CHEMBL297371

SMILES COC(=O)[C@@H](CNC(=O)c1ccc(cc1)-c1ccccc1)Cc1cccc(c1)C(N)=N

InChI Key InChIKey=KSIJTKXNOBKZFG-JOCHJYFZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114532   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114532((R)-2-{[(Biphenyl-4-carbonyl)-amino]-methyl}-3-(3-...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114532((R)-2-{[(Biphenyl-4-carbonyl)-amino]-methyl}-3-(3-...)
Affinity DataKi:  20nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114532((R)-2-{[(Biphenyl-4-carbonyl)-amino]-methyl}-3-(3-...)
Affinity DataKi:  230nMAssay Description:In vitro inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114532((R)-2-{[(Biphenyl-4-carbonyl)-amino]-methyl}-3-(3-...)
Affinity DataKi: >3.95E+3nMAssay Description:In vitro inhibitory activity against human Coagulation factor IIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed