BDBM50114585 (R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL47203

SMILES: CN1CCN(CC1)[C@H]1CC[C@H](CC1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key: InChIKey=FDVSOQRNTAPCHB-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50114585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50114585 ((R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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