BDBM50114653 (1E)-1-(3,4-dichlorophenyl)ethan-1-one thiosemicarbazone::CHEMBL90512
SMILES CC(=NNC(N)=S)c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=WLYQLQVFJXFMJD-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50114653
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma cruzi Cruzain using Z-FR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen 2 cruzain incubated for 5 mins folllowed by Z-Phe-Arg-AMC substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of epimastigote form of Trypanosoma cruzi Tulahuen 2 cruzain assessed as reduction in 7-amino-4-methylcoumarin release incubated for 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen 2 cruzain incubated for 5 mins folllowed by Z-Phe-Arg-AMC substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of epimastigote form of Trypanosoma cruzi Tulahuen 2 cruzain assessed as reduction in 7-amino-4-methylcoumarin release incubated for 20 mi...More data for this Ligand-Target Pair