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BDBM50114767 2-Chloro-3-(2-pyridin-3-yl-vinyl)-5-(pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL316539

SMILES: Clc1ncc(OCC2CCCN2)cc1\C=C\c1cccnc1

InChI Key: InChIKey=LDMDYPWUDDFQHB-AATRIKPKNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114767   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))
BDBM50114767
PNG
(2-Chloro-3-(2-pyridin-3-yl-vinyl)-5-(pyrrolidin-2-...)
Show SMILES Clc1ncc(OCC2CCCN2)cc1\C=C\c1cccnc1
Show InChI InChI=1/C17H18ClN3O/c18-17-14(6-5-13-3-1-7-19-10-13)9-16(11-21-17)22-12-15-4-2-8-20-15/h1,3,5-7,9-11,15,20H,2,4,8,12H2/b6-5+
PDB
MMDB

KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
28n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-imidacloprid in Drosophila


J Med Chem 45: 2841-9 (2002)


Article DOI: 10.1021/jm010550n
BindingDB Entry DOI: 10.7270/Q2FN15JT
More data for this
Ligand-Target Pair