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BDBM50115063 1-Adamantan-1-yl-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL301503

SMILES: Fc1ccc(CC2CCN(CCCNC(=O)NC34CC5CC(CC(C5)C3)C4)CC2)cc1

InChI Key: InChIKey=NAPUJZZCCVJTMV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115063   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50115063
PNG
(1-Adamantan-1-yl-3-{3-[4-(4-fluoro-benzyl)-piperid...)
Show SMILES Fc1ccc(CC2CCN(CCCNC(=O)NC34CC5CC(CC(C5)C3)C4)CC2)cc1
Show InChI InChI=1S/C26H38FN3O/c27-24-4-2-19(3-5-24)12-20-6-10-30(11-7-20)9-1-8-28-25(31)29-26-16-21-13-22(17-26)15-23(14-21)18-26/h2-5,20-23H,1,6-18H2,(H2,28,29,31)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin


Bioorg Med Chem Lett 12: 1785-9 (2002)


Article DOI: 10.1016/s0960-894x(02)00206-8
BindingDB Entry DOI: 10.7270/Q28W3CN8
More data for this
Ligand-Target Pair