BDBM50115162 6-(4-Chloro-phenyl)-4-piperidin-1-yl-5,6,7,8-tetrahydro-pteridin-2-ylamine::CHEMBL101879

SMILES Nc1nc2NCC(Nc2c(n1)N1CCCCC1)c1ccc(Cl)cc1

InChI Key InChIKey=VLFZJRDUEIBKCU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115162   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115162(6-(4-Chloro-phenyl)-4-piperidin-1-yl-5,6,7,8-tetra...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115162(6-(4-Chloro-phenyl)-4-piperidin-1-yl-5,6,7,8-tetra...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115162(6-(4-Chloro-phenyl)-4-piperidin-1-yl-5,6,7,8-tetra...)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115162(6-(4-Chloro-phenyl)-4-piperidin-1-yl-5,6,7,8-tetra...)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed