BDBM50115209 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)phenyl)urea::1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-urea::1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)phenyl]urea::BIRB-796 derivative, 14::CHEMBL101035

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)cc1)C(C)(C)C

InChI Key: InChIKey=FRZNJFWQVYAVCE-UHFFFAOYSA-N

Data: 7 IC50  1 Kd  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50115209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Putative glycogen synthase kinase 3 alpha (Corn smut fungus)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glycogen synthase kinase-3 beta (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00390	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50115209 (CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair