BDBM50115579 (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid (0.25H2O)::CHEMBL16326::CHEMBL19332::CHEMBL467389::Sacchettini_CTRL

SMILES: c1ccc(cc1)C(=O)CC(=O)C(=O)O

InChI Key: InChIKey=JGKFWCXVYCDKDU-UHFFFAOYSA-N

Data: 5 KI  24 IC50  1 EC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50115579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Influenza A virus (strain A/X-31 H3N2))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (HCV)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		6.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50115579 (CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...) Show SMILES Show InChI	GoogleScholar	UniChem		7.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair