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BDBM50115732 CHEMBL294467::Sodium vanadate

SMILES: [O-][V](=O)=O

InChI Key: InChIKey=ALTWGIIQPLQAAM-UHFFFAOYSA-N

Data: 1 KI  2 IC50

PDB links: 12 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115732   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase


(Homo sapiens (Human))
BDBM50115732
PNG
(CHEMBL294467 | Sodium vanadate)
Show SMILES [O-][V](=O)=O
Show InChI InChI=1S/3O.V/q;;-1;
PDB
MMDB

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5.40E+5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details

BindingDB Entry DOI: 10.7270/Q28S4SV8
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50115732
PNG
(CHEMBL294467 | Sodium vanadate)
Show SMILES [O-][V](=O)=O
Show InChI InChI=1S/3O.V/q;;-1;
PDB
MMDB

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Article
PubMed
n/an/a 8.05E+3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluoreacein diphosphate (FDP) as a substrate


Bioorg Med Chem Lett 12: 1941-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00331-1
BindingDB Entry DOI: 10.7270/Q2QZ2999
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50115732
PNG
(CHEMBL294467 | Sodium vanadate)
Show SMILES [O-][V](=O)=O
Show InChI InChI=1S/3O.V/q;;-1;
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
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antibodypedia
GoogleScholar
Purchase

CHEBI
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin)


Bioorg Med Chem Lett 23: 297-300 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.097
BindingDB Entry DOI: 10.7270/Q2CJ8FS8
More data for this
Ligand-Target Pair