BDBM50116030 3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]-pyridin-2-ylamine::CHEMBL291834

SMILES Nc1nc(F)c(F)c(-c2nc(c(o2)-c2ccncc2)-c2ccc(F)cc2)c1F

InChI Key InChIKey=UXQCYJLHSATORC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116030   

TargetMitogen-activated protein kinase 14(Mouse)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116030(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116030(3,5,6-Trifluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed