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BDBM50116116 (2,5-Dimethyl-3-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl)-dipropyl-amine::CHEMBL304048

SMILES: CCCN(CCC)c1nc(C)nc2c(-c3ccccc3)n(C)nc12

InChI Key: InChIKey=IHFUEVMLVQBJQL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116116   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50116116
PNG
((2,5-Dimethyl-3-phenyl-2H-pyrazolo[4,3-d]pyrimidin...)
Show SMILES CCCN(CCC)c1nc(C)nc2c(-c3ccccc3)n(C)nc12
Show InChI InChI=1S/C19H25N5/c1-5-12-24(13-6-2)19-17-16(20-14(3)21-19)18(23(4)22-17)15-10-8-7-9-11-15/h7-11H,5-6,12-13H2,1-4H3
PDB
MMDB

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Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cells


Bioorg Med Chem Lett 12: 2133-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00358-x
BindingDB Entry DOI: 10.7270/Q2SQ8ZPK
More data for this
Ligand-Target Pair