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BDBM50116675 4,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine::CHEMBL75905

SMILES: CC1CN=C(N)C=C1C

InChI Key: InChIKey=XSBPJMLMXBSYJN-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116675   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116675
PNG
(4,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CN=C(N)C=C1C
Show InChI InChI=1/C7H12N2/c1-5-3-7(8)9-4-6(5)2/h3,6H,4H2,1-2H3,(H2,8,9)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 520n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00455-9
BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116675
PNG
(4,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CN=C(N)C=C1C
Show InChI InChI=1/C7H12N2/c1-5-3-7(8)9-4-6(5)2/h3,6H,4H2,1-2H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00455-9
BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair