BDBM50116730 CHEMBL78851::[3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]-3-(3,4-dichloro-phenyl)-4-[(Z)-methoxyimino]-pentyl}-piperidin-4-yl)-2-oxo-2,3-dihydro-benzoimidazol-1-yl]-acetic acid methyl ester

SMILES CO\N=C(/CN(C)C(=O)c1cc(Cl)cc(Cl)c1)[C@H](CCN1CCC(CC1)n1c2ccccc2n(CC(=O)OC)c1=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=AXOFNMUYIHBQIG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116730   

TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116730([3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116730([3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116730([3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]...)
Affinity DataKi:  29nMAssay Description:Binding affinity against recombinant human tachykinin receptor 3 in CHO cells using [125I][MePhe]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed