BDBM50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570

SMILES: CCCN[C@H]1CCc2c(sc(n2)N)C1

InChI Key: InChIKey=FASDKYOPVNHBLU-UHFFFAOYSA-N

Data: 69 KI  9 IC50  7 Kd  22 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 107 hits for monomerid = 50116766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(4) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0149	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0149	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0258	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	166	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.813	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50116766 ((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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