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BDBM50116781 CHEMBL2263369

SMILES: Nc1ccccc1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=QRNJDQFLQROCKF-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid desaturase 1


(Homo sapiens (Human))
BDBM50116781
PNG
(CHEMBL2263369)
Show SMILES Nc1ccccc1C(=O)Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H10ClFN2O/c14-10-7-8(5-6-11(10)15)17-13(18)9-3-1-2-4-12(9)16/h1-7H,16H2,(H,17,18)
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Similars

Article
PubMed
n/an/a 155n/an/an/an/an/an/a



Lexicon Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of liver delta-5 desaturase (unknown origin)


Bioorg Med Chem Lett 25: 3836-9 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.066
BindingDB Entry DOI: 10.7270/Q2MP552Z
More data for this
Ligand-Target Pair