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BDBM50117453 1-(1,2-Diphenyl-ethyl)-3-(3-hydroxy-propyl)-urea::CHEMBL126106

SMILES: OCCCNC(=O)NC(Cc1ccccc1)c1ccccc1

InChI Key: InChIKey=ZLWPRXIKLICWMA-UHFFFAOYNA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117453   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50117453
PNG
(1-(1,2-Diphenyl-ethyl)-3-(3-hydroxy-propyl)-urea |...)
Show SMILES OCCCNC(=O)NC(Cc1ccccc1)c1ccccc1
Show InChI InChI=1/C18H22N2O2/c21-13-7-12-19-18(22)20-17(16-10-5-2-6-11-16)14-15-8-3-1-4-9-15/h1-6,8-11,17,21H,7,12-14H2,(H2,19,20,22)
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cells


J Med Chem 45: 3794-804 (2002)


Article DOI: 10.1021/jm0201767
BindingDB Entry DOI: 10.7270/Q2MW2GG0
More data for this
Ligand-Target Pair