BDBM50117553 8-Chloro-6,7-difluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::CHEMBL87219

SMILES NC1=Nc2c(F)c(F)c(Cl)cc2[C@H]2CCC[C@@H]12

InChI Key InChIKey=KIVCYMMBRBXVPG-NTSWFWBYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117553   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117553(8-Chloro-6,7-difluoro-2,3,3a,9b-tetrahydro-1H-cycl...)
Affinity DataIC50:  7.80E+4nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117553(8-Chloro-6,7-difluoro-2,3,3a,9b-tetrahydro-1H-cycl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117553(8-Chloro-6,7-difluoro-2,3,3a,9b-tetrahydro-1H-cycl...)
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro inhibition of endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed