BDBM50117559 8-Fluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::CHEMBL86040

SMILES NC1=Nc2ccc(F)cc2[C@H]2CCC[C@@H]12

InChI Key InChIKey=SJEDGBZMJTUDPB-DTWKUNHWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117559   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117559(8-Fluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quin...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117559(8-Fluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quin...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117559(8-Fluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quin...)
Affinity DataIC50:  110nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed