BDBM50117567 (3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::CHEMBL86961

SMILES NC1=Nc2c(F)c(F)ccc2[C@H]2CCC[C@@H]12

InChI Key InChIKey=CXBOTECYGADDIW-HTRCEHHLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50117567   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibition of endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  5.10E+3nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Schering

Curated by ChEMBL
LigandPNGBDBM50117567((3aR,9bS)-6,7-Difluoro-2,3,3a,9b-tetrahydro-1H-cyc...)
Affinity DataIC50:  680nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed