BDBM50118027 4-[1-(2,2-Dimethyl-propyl)-azetidine-3-carbonyl]-3-isopropyl-1-methanesulfonyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one; hydrochloride::CHEMBL554013
SMILES CC(C)[C@H]1[C@H]2[C@@H](CCN2C(=O)C2CN(CC(C)(C)C)C2)N(C1=O)S(C)(=O)=O
InChI Key InChIKey=PDKMPCTWJJRYEQ-OWCLPIDISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50118027
Affinity DataKi: 1.70nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 1.73nM Kon: 0.0000109M-1s-1 Koff: 6.31E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against trypsin using selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against cathepsin G using selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The compound was evaluated for its inhibitory activity against dog neutrophil elastase using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKon: 1.09E+7M-1s-1pH: 7.4Assay Description:Association rate constant at pH 7.4 against ElastaseMore data for this Ligand-Target Pair