BDBM50118165 CHEMBL3613662

SMILES COc1nn(Cc2cccc(OCc3ccccc3)c2)c(=O)o1

InChI Key InChIKey=ZZCFHWVVOIYUPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118165   

TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118165(CHEMBL3613662)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118165(CHEMBL3613662)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118165(CHEMBL3613662)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118165(CHEMBL3613662)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed