BDBM50118260 9-(4-Hydroxy-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-fluoren-9-ol::CHEMBL130668
SMILES Oc1ccc(cc1)C1(O)N2CCCN=C2c2ccccc12
InChI Key InChIKey=NFNRNOMETYDQMI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50118260
Affinity DataKi: 77nMAssay Description:Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 87.1nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of NE uptake in HEK cells expressing human noradrenaline transporter (hNET)More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-HT uptake in HEK cells expressing human serotonin transporter (hSERT)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)More data for this Ligand-Target Pair