BDBM50118703 CHEMBL109783::N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1

InChI Key: InChIKey=OQFCXJDXHCDLHX-UHFFFAOYSA-N

Data: 17 KI  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50118703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1B adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rabbit)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Hamster)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Hamster)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Hamster)	BDBM50118703 (N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair