BDBM50118785 2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid::2-(carboxyformamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid::CHEMBL138151

SMILES OC(=O)C(=O)Nc1sc2CCCCCc2c1C(O)=O

InChI Key InChIKey=DJNYYMKZRUYSIK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118785   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  1.19E+4nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  1.20E+4nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Graduate University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  3.20E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118785(2-(Oxalyl-amino)-5,6,7,8-tetrahydro-4H-cyclohepta[...)
Affinity DataKi:  4.00E+5nMpH: 5.5Assay Description:Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed