BDBM50119203 (S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino]-pentanoic acid ((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino]-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL100405

SMILES CC(C)C[C@H](NC(=O)COc1ccc2ccccc2c1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=BSVUOPHXZOKMKE-KJMDXERQSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50119203   

TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  940nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  944nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-1 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-8 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  8.87E+3nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-8 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  940nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-6 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibitory concentration of compound required against Caspase-6 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  8.87E+3nMAssay Description:Inhibitory concentration of compound required against Caspase-7 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119203((S)-4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino...)
Affinity DataIC50:  8.87E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed