BDBM50119557 CHEMBL3617575

SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2cc(Cl)cc(c2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1

InChI Key InChIKey=KPVSJEREKOMPTE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119557   

TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50119557(CHEMBL3617575)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]-glucagon from full length human glucagon receptor expressed in HEK293 cell membranes after 2 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50119557(CHEMBL3617575)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human glucagon receptor expressed in HEK293 cell membranes assessed as inhibition of glucagon-stimulated intracellular cAMP fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed