BDBM50119640 2-(6-Chloro-5-fluoro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::CHEMBL54686

SMILES Fc1cc(cnc1Cl)[C@H]1CC2CCC1N2

InChI Key InChIKey=PKAQUVZVSSGSES-CCNFQMFXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119640   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50119640(2-(6-Chloro-5-fluoro-pyridin-3-yl)-7-aza-bicyclo[2...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of [3H]-epibatidine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50119640(2-(6-Chloro-5-fluoro-pyridin-3-yl)-7-aza-bicyclo[2...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of [125I]-iodo-MLA binding to Nicotinic acetylcholine receptor alpha7 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50119640(2-(6-Chloro-5-fluoro-pyridin-3-yl)-7-aza-bicyclo[2...)
Affinity DataKi:  3.43nMAssay Description:Inhibition of [125I]- iodo-MLA binding at the Nicotinic acetylcholine receptor alpha-7 (nAChR) in male rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed